Registration

Welcome & Introduction

Session I (AOC session VI) : food, inflammation and cancer research - Chairman : Pr V. Théodorou, Dr C. Carpéné

Invited speaker : Dr Robert Casero, Johns Hopkins Hospital, Baltimore (USA)

The role of spermine oxidase in inflammation-associated carcinogenesis

Selected oral communications

M. Alexandru Mateescu: Enzymatically assisted bio-elimination of histamine in treatment of enteric dysfunctions

C. Carpéné: Serotonin oxidation and adipogenic effects in adipocytes

N. Bastide: An in vivo study of potential agents underlying the promotive effect of red meat: demonstration of the major role of heme and lipid peroxidation in two animals models of carcinogenesis

O. Martin: Suppression by calcium and α-tocopherol of cured meat promotion of faecal biomarkers in human and rat is associated to protection against promotion of dimethylhydrazine-induced mucin-depleted foci in rat colons

Coffee Break - Poster session & Exhibition

Selected oral communications

Thi H.Y. Nguyen: Leave extracts and compounds isolated from crinum latifolium activate the differenciation of blood mononuclear cells

S. Da Silva: Interactions between the probiotic lactobacillus farciminis and the rat intestinal mucus under physiological and pathophysiological conditions

S. Agostini: Protective effect of a fermented milk dairy product containing bifidobacterium lactis CNCM I-2494 on gut immune barrier impairment promoted by acute stress in rats

L. Moussa: Protective effects of a treatment by a soy germ fermented ingredient on colonic inflammation-associated hyperpermeability and hyperalgesia in female rats: involvement of estrogen receptors

J. Grimoud: Investigation of prebiotic characteristics of innovative fructooligosaccharides: probiotics metabolization and enteropathogens inhibition

End Session I – Concluding remarks AOC 2012

Wine and Cheese Party at Ecole d’Ingénieurs de PURPAN

Session II : Metabolic disorders - Chairman : Pr Max Lafontan

Invited Speaker : Pr Patrice D. Cani, Catholic University of Louvain (Belgium) :

"Gut microbiota, obesity and type 2 diabetes: from bench to bedside”

Selected oral communications

S. Handgraaf: Prevention of obesity and insulin resistance by estrogens: crucial role of ERα activation function 2 (AF-2)

S. Gomez-Zorita: Effects of resveratrol on glucose uptake and on triacylglycerol breakdown in human adipocytes

Coffee Break - Poster session & Exhibition

Selected oral communications

A. Drougard: Central apelin mediates the transition from normal to diabetic state: the liver as a target

C. Bertrand: Effects of eicosapentaenoic acid (EPA) on muscle apelin expression and on insulin sensitivity in high-fat fed mice

S. Ducheix: LXR deficiency protects from steatosis induced by dietary fructose

M. Dormishian: Endothelium-specific prokineticin receptor 1 inactivation leads to endothelial dysfunction and metabolic syndrome-like disorders

H. Ibrahim: Erythrocytes as a potential metabolic site for isatogen derivatives

Lunch - Poster Session & Exhibition

Session III : Endocrine disruption - Chairman : Dr Jean-Pierre Cravedi

Invited Speaker : Pr Ana Soto, Tufts University of Boston (USA) :

Fetal xenoestrogen exposure syndrome: does cancer start in the womb?

Selected oral communications

S. Ménard: Perinatal exposure to low doses of the food endocrine disruptor bisphenol A impairs oral tolerance and sensitization in offspring rats at adulthood

N. Cabaton: Metabonomics reveal metabolic changes in CD1 mice perinatally exposed to low doses of bisphenol A (BPA)

T. Corbel: Characterization of maternal and fetal bisphenol A disposition in a physiologically-based sheep model

Coffee Break - Poster session & Exhibition

Selected oral communications

A. Jondeau-Cabaton: Endocrine disruptors characterized from a complex matrix using bioanalytical methods: ER affinity columns and LC-HRMS

A. Marmugi: Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver

K. Jédéon: Impact of ingested endocrine disruptors (ED) on tooth enamel mineralization

B. B. Roques: Contribution of the nuclear receptors PXR and car to gene expression modulations induced by fipronil in rodent liver

End Session III – Concluding remarks SAS 2012